Metal(loid) contamination of agricultural soils has become an alarming issue due to its detrimental impacts on soil health and global agricultural production. Therefore, environmentally sustainable and cost-effective solutions are urgently required for soil remediation. Biochar, particularly nano-biochar, exhibits superior and highperformance capabilities in the remediation of metal(loid)-contaminated soil, owing to its unique structure and large surface area. Current researches on nano-biochar mainly focus on safety design and property improvement, with limited information available regarding the impact of nano-biochar on soil ecosystems and crop defense mechanisms in metal(loid)-contaminated soils. In this review, we systematically summarized recent progress in the application of nano-biochar for remediation of metal(loid)-contaminated soil, with a focus on possible factors influencing metal(loid) uptake and translocation in soil-crop systems. Additionally, we conducted the potential/ related mechanisms by which nano-biochar can mitigate the toxic impacts of metal(loid) on crop production and security. Furthermore, the application of nano-biochar in field trials and existing challenges were also outlined. Future studies should integrate agricultural sustainability and ecosystem health targets into biochar design/selection. This review highlighted the potential of nano-biochar as a promising soil amendment for enhancing the remediation of metal(loid)-contaminated agricultural soils, thereby promoting the synthesis and development of highly efficient nano-biochar towards achieving environmental sustainability.